BDBM137345 US8871790, 431

SMILES CC(C)N1CCc2nc([nH]c2CC1)-c1cc(C(=O)N2CCC(CC2)c2ccc(cc2)C#N)c(C)cc1C

InChI Key InChIKey=OZXWUUVGOJNLNB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 137345   

TargetFatty acid synthase(Human)
Sagimet Biosciences

US Patent
LigandPNGBDBM137345(US8871790, 431 | US20250017938, Compound 001-431)
Affinity DataIC50: 25nMAssay Description:Determination of FASN biochemical activity: The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetFatty acid synthase(Human)
Sagimet Biosciences

US Patent
LigandPNGBDBM137345(US8871790, 431 | US20250017938, Compound 001-431)
Affinity DataIC50: 25nMAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent