BDBM13755 (1R,3R,4S,7S)-4-(2-methyl-2-phenoxypropanamido)adamantane-1-carboxylic acid::adamantane ether 5

SMILES CC(C)(Oc1ccccc1)C(=O)N[C@H]1C2C[C@@H]3C[C@@H]1C[C@](C3)(C2)C(O)=O

InChI Key

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 13755   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM13755((1R,3R,4S,7S)-4-(2-methyl-2-phenoxypropanamido)ada...)
Affinity DataIC50: 38.9nMAssay Description:Inhibition of 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM13755((1R,3R,4S,7S)-4-(2-methyl-2-phenoxypropanamido)ada...)
Affinity DataIC50: 39nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

LigandPNGBDBM13755((1R,3R,4S,7S)-4-(2-methyl-2-phenoxypropanamido)ada...)
Affinity DataIC50: 119nMAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mouse)
Abbott Laboratories

LigandPNGBDBM13755((1R,3R,4S,7S)-4-(2-methyl-2-phenoxypropanamido)ada...)
Affinity DataIC50: 1.50E+3nMAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Abbott Laboratories

LigandPNGBDBM13755((1R,3R,4S,7S)-4-(2-methyl-2-phenoxypropanamido)ada...)
Affinity DataIC50: 1.70E+4nMAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed