BDBM13815 ({4-[(4E)-2-(1H-1,2,3-benzotriazol-1-yl)-2,5-diphenylpent-4-en-1-yl]phenyl}difluoromethyl)phosphonic acid::CHEMBL416145::benzotriazole phenyldifluoromethylphosphonic acid compound 2

SMILES OP(O)(=O)C(F)(F)c1ccc(CC(C\C=C\c2ccccc2)(c2ccccc2)n2nnc3ccccc23)cc1

InChI Key InChIKey=DZAZPBQYQDQTEN-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 13815   

TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Human)
Merck Frosst Center For Therapeutic Research

LigandPNGBDBM13815(({4-[(4E)-2-(1H-1,2,3-benzotriazol-1-yl)-2,5-diphe...)
Affinity DataIC50: 109nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Merck Frosst Center For Therapeutic Research

LigandPNGBDBM13815(({4-[(4E)-2-(1H-1,2,3-benzotriazol-1-yl)-2,5-diphe...)
Affinity DataIC50: 95nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM13815(({4-[(4E)-2-(1H-1,2,3-benzotriazol-1-yl)-2,5-diphe...)
Affinity DataIC50: 49nMAssay Description:Inhibitory activity against protein tyrosine phosphatase 1B (PTP1B) was determined in fluorescein diphosphate (FDP) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM13815(({4-[(4E)-2-(1H-1,2,3-benzotriazol-1-yl)-2,5-diphe...)
Affinity DataIC50: 460nMAssay Description:Inhibitory activity against Protein tyrosine phosphatase 1B (PTP1B) over-expressed in intact Sf9 cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Merck Frosst Center For Therapeutic Research

LigandPNGBDBM13815(({4-[(4E)-2-(1H-1,2,3-benzotriazol-1-yl)-2,5-diphe...)
Affinity DataIC50: 49nMAssay Description:Inhibitory activity against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM13815(({4-[(4E)-2-(1H-1,2,3-benzotriazol-1-yl)-2,5-diphe...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory activity against CD45 protein-tyrosine phosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed