BDBM139196 US8889668, I23

SMILES Cc1cc(ccc1-c1ccccc1C(F)(F)F)-c1nc(no1)-c1ccccc1OC(F)(F)F

InChI Key InChIKey=YHZXYFNSENVHTC-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 139196   

TargetSphingosine 1-phosphate receptor 1(Human)
Merck Serono

US Patent
LigandPNGBDBM139196(US8889668, I23)
Affinity DataKi:  16nM ΔG°:  -9.88kcal/molepH: 7.4 T: 2°CAssay Description:Receptor binding assay: Membranes were prepared from CHO cells expressing S1P1 or S1P3 for use in ligand and 35S-GTPgammaS binding studies. Cells wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details
US Patent