BDBM139198 US8889668, I26

SMILES COc1ccccc1c4noc(c3ccc(c2ccccc2C)c([N+](=O)[O-])c3)n4

InChI Key InChIKey=KWGIMEXFQIDRBU-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 139198   

TargetSphingosine 1-phosphate receptor 1(Human)
Merck Serono

US Patent
LigandPNGBDBM139198(US8889668, I26)
Affinity DataKi:  2nM ΔG°:  -11.0kcal/molepH: 7.4 T: 2°CAssay Description:Receptor binding assay: Membranes were prepared from CHO cells expressing S1P1 or S1P3 for use in ligand and 35S-GTPgammaS binding studies. Cells wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details
US Patent