BDBM13946 APC-13417::[amino({2-[(phenylcarbamoyl)amino]-1H-1,3-benzodiazol-5-yl})methylidene]azanium

SMILES NC(=[NH2+])c1ccc2nc(NC(=O)Nc3ccccc3)[nH]c2c1

InChI Key InChIKey=PTSCFXWDZPISNU-UHFFFAOYSA-O

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 13946   

TargetSerine protease 1(Bovine)
Axys Pharmaceuticals

LigandPNGBDBM13946([amino({2-[(phenylcarbamoyl)amino]-1H-1,3-benzodia...)
Affinity DataKi:  7.20E+3nM ΔG°:  -6.94kcal/molepH: 7.6 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2007
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Axys Pharmaceuticals

LigandPNGBDBM13946([amino({2-[(phenylcarbamoyl)amino]-1H-1,3-benzodia...)
Affinity DataKi:  3.00E+4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2007
Entry Details Article
PubMed
TargetProthrombin(Human)
Axys Pharmaceuticals

LigandPNGBDBM13946([amino({2-[(phenylcarbamoyl)amino]-1H-1,3-benzodia...)
Affinity DataKi:  4.90E+4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2007
Entry Details Article
PubMed