BDBM139717 US8895549, 2::US9675616, 2 N-(8-{[(2R)-2-hydroxy-3-(morpholin-4-yl)propyl]oxy}-7-methoxy-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl)pyridine-1-carboxamide

SMILES COc1c(OC[C@H](O)CN2CCOCC2)ccc2C3=NCCN3C(NC(=O)c3cccnc3)=Nc12

InChI Key InChIKey=YTWYXKYMMKOBOM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 139717   

LigandPNGBDBM139717(US8895549, 2 | US9675616, 2 N-(8-{[(2R)-2-hydroxy-...)
Affinity DataIC50: 2.98nMAssay Description:As reagents for the kinase reaction itself and the quantification of the reaction product, the PI3-Kinase HTRF Assay kit from Millipore (#33-017) was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2015
Entry Details
US Patent

LigandPNGBDBM139717(US8895549, 2 | US9675616, 2 N-(8-{[(2R)-2-hydroxy-...)
Affinity DataIC50: 30nMAssay Description:For the assay 50 nL of a 80-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384-well microtiter plate (G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM139717(US8895549, 2 | US9675616, 2 N-(8-{[(2R)-2-hydroxy-...)
Affinity DataIC50: 30nMAssay Description:For the assay 50 mL of a 80-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384-well microtiter plate (G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent