BDBM14090 (2S)-N-[(2S)-1-(1,3-benzothiazol-2-yl)-6-carbamimidamido-1-oxohexan-2-yl]-1-[(2R)-2-(methylamino)-3-phenylpropanoyl]pyrrolidine-2-carboxamide::2-ketobenzothiazole 30

SMILES [#6]-[#7]-[#6@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-c1nc2ccccc2s1

InChI Key InChIKey=ARKHIMVIVBJTLM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 14090   

TargetProthrombin(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM14090((2S)-N-[(2S)-1-(1,3-benzothiazol-2-yl)-6-carbamimi...)
Affinity DataIC50: 8.40E+3nMAssay Description:Thrombin-catalyzed hydrolysis rates were measured spectrophotometrically using human alpha-thrombin, a chromogenic substrate in aqueous buffer, and a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2007
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM14090((2S)-N-[(2S)-1-(1,3-benzothiazol-2-yl)-6-carbamimi...)
Affinity DataIC50: 630nMAssay Description:Thrombin-catalyzed hydrolysis rates were measured spectrophotometrically using human alpha-thrombin, a chromogenic substrate in aqueous buffer, and a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2007
Entry Details Article
PubMed