BDBM14184 3-thia-13-azahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,22}]tricosa-1(16),2(10),4(9),5,7,11(15),17(22),18,20-nonaen-12-one::Indenyl[2,3-c]benzothienyl[2,3-e]isoindol-3-one::Lactam Analog 38

SMILES O=C1NCc2c-3c(Cc4ccccc-34)c3sc4ccccc4c3c12

InChI Key InChIKey=GSHILQCUENBVBZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 14184   

LigandPNGBDBM14184(Indenyl[2,3-c]benzothienyl[2,3-e]isoindol-3-one | ...)
Affinity DataIC50: 615nMpH: 7.2 T: 2°CAssay Description:The MLK1, MLK2, and MLK3 assays were performed using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. IC50 values were calculate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2007
Entry Details Article
PubMed
LigandPNGBDBM14184(Indenyl[2,3-c]benzothienyl[2,3-e]isoindol-3-one | ...)
Affinity DataIC50: 110nMAssay Description:The MLK1, MLK2, and MLK3 assays were performed using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. IC50 values were calculate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2007
Entry Details Article
PubMed