BDBM142147 US8933079, 2.5

SMILES CN(C)Cc1ccc(C(=O)Cn2ccc(OCc3ccc(F)cn3)cc2=O)c(C)c1

InChI Key InChIKey=QKLFVKUALMUOSG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 142147   

TargetMelanin-concentrating hormone receptor 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM142147(US8933079, 2.5)
Affinity DataIC50: 70nMpH: 7.0Assay Description:Membranes from CHO/Galpha16 cells stably transfected with human hMCH-1R are resuspended using a syringe (needle 0.6x25 mm) and diluted in test buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
Go to US Patent

TargetMelanin-concentrating hormone receptor 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM142147(US8933079, 2.5)
Affinity DataIC50: 70nMAssay Description:Displacement of [125I]-MCH from human MCH-R1 expressed in CHO/Galpha16 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed