BDBM142708 US8937084, 10

SMILES COc1ccc2C[C@@H]3[C@@H]4CNCC[C@]4(CCN3CC3CC3)c2c1

InChI Key InChIKey=UIBZEVKKIICJJV-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 142708   

TargetKappa-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM142708(US8937084, 10)
Affinity DataKi:  37nM ΔG°:  -11.0kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand dose-displacement binding assays for u-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg membrane...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
Go to US Patent