BDBM142740 US8937095, 2

SMILES CN(C)Cc1ccc(N\C(=C2/C(=O)Nc3cc(ccc23)C#CC(=O)NCC(F)F)c2ccccc2)cc1

InChI Key InChIKey=DHVWLRAQAXNGGF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 142740   

TargetAurora kinase B-B(African clawed frog)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM142740(US8937095, 2)
Affinity DataIC50: 7nMpH: 7.6Assay Description:The ATP-KM value of the complex is 61 uM. The kinase assays are run in the presence of 100 uM ATP using 10 uM of a substrate peptide. pAUB-IN847 was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM142740(US8937095, 2)
Affinity DataIC50: 6nMpH: 7.6Assay Description:The ATP-KM value of the complex is 61 uM. The kinase assays are run in the presence of 100 uM ATP using 10 uM of a substrate peptide. pAUB-IN847 was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
Go to US Patent