BDBM144345 US8969348, {4-[(1-Methyl-1H-indol-3-yl)methyl]-1-oxophthalazin-2(1H)-yl}(phenyl)acetic acid

SMILES Cn1cc(Cc2nn(C(C(O)=O)c3ccccc3)c(=O)c3ccccc23)c2ccccc12

InChI Key InChIKey=JXEAVXZALMHYOT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 144345   

TargetChymase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM144345(US8969348, {4-[(1-Methyl-1H-indol-3-yl)methyl]-1-o...)
Affinity DataIC50: 360nMpH: 8.0Assay Description:Chymase assays were performed in a total volume of 15 uL in Corning black opaque 384-well microtiter plates with a non-binding surface (Corning, N.Y....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent