BDBM14531 N-[(4-carbamimidoylphenyl)methyl]-2-[5-chloro-2-oxo-6-phenyl-3-(prop-2-yn-1-ylamino)-1,2-dihydropyrazin-1-yl]acetamide::Pyrazinone Analog 28e

SMILES NC(=N)c1ccc(CNC(=O)Cn2c(c(Cl)nc(NCC#C)c2=O)-c2ccccc2)cc1

InChI Key InChIKey=AFTBQQXBKRFNFS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 14531   

TargetCoagulation factor VII(Human)
Pharmacia

LigandPNGBDBM14531(N-[(4-carbamimidoylphenyl)methyl]-2-[5-chloro-2-ox...)
Affinity DataIC50: 720nMAssay Description:Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2007
Entry Details Article
PubMed
TargetProthrombin(Human)
Pharmacia

LigandPNGBDBM14531(N-[(4-carbamimidoylphenyl)methyl]-2-[5-chloro-2-ox...)
Affinity DataIC50: 3.00E+3nMAssay Description:Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2007
Entry Details Article
PubMed