BDBM14591 N-{3-[1-({[(4-carbamimidoylphenyl)methyl]carbamoyl}methyl)-3-chloro-6-oxo-5-[(2-phenylethyl)amino]-1,6-dihydropyrazin-2-yl]phenyl}-2,2,2-trifluoroacetamide::Pyrazinone Analog 33d

SMILES NC(=N)c1ccc(CNC(=O)Cn2c(c(Cl)nc(NCCc3ccccc3)c2=O)-c2cccc(NC(=O)C(F)(F)F)c2)cc1

InChI Key InChIKey=RISTVLHHKSEXTE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 14591   

TargetCoagulation factor VII(Human)
Pharmacia

LigandPNGBDBM14591(N-{3-[1-({[(4-carbamimidoylphenyl)methyl]carbamoyl...)
Affinity DataIC50: 450nMAssay Description:Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2007
Entry Details Article
PubMed
TargetProthrombin(Human)
Pharmacia

LigandPNGBDBM14591(N-{3-[1-({[(4-carbamimidoylphenyl)methyl]carbamoyl...)
Affinity DataIC50: 2.00E+3nMAssay Description:Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2007
Entry Details Article
PubMed