BDBM14598 N-[(4-carbamimidoylphenyl)methyl]-2-{2-methoxy-6-phenyl-3-[(2-phenylethyl)amino]phenyl}acetamide::N-{4-[Amino(imino)methyl]benzyl}-2-{3-methoxy-4-[(2-phenylethyl)amino]-1,1-biphenyl-2-yl}acetamide::Substituted Benzene Analog 50d

SMILES COc1c(NCCc2ccccc2)ccc(c1CC(=O)NCc1ccc(cc1)C(N)=N)-c1ccccc1

InChI Key InChIKey=GXOLLDCZLSCRTK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 14598   

TargetProthrombin(Human)
Pharmacia

LigandPNGBDBM14598(N-[(4-carbamimidoylphenyl)methyl]-2-{2-methoxy-6-p...)
Affinity DataIC50: 9.50E+3nMpH: 8.0 T: 2°CAssay Description:Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2007
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Pharmacia

LigandPNGBDBM14598(N-[(4-carbamimidoylphenyl)methyl]-2-{2-methoxy-6-p...)
Affinity DataIC50: 2.50E+4nMpH: 8.0 T: 2°CAssay Description:Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Pharmacia

LigandPNGBDBM14598(N-[(4-carbamimidoylphenyl)methyl]-2-{2-methoxy-6-p...)
Affinity DataIC50: 3.00E+4nMpH: 8.0 T: 2°CAssay Description:Human Factor Xa and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2007
Entry Details Article
PubMed