BDBM14600 N-[(4-carbamimidoylphenyl)methyl]-2-{2-hydroxy-6-phenyl-3-[(2-phenylethyl)amino]phenyl}acetamide::N-{4-[Amino(imino)methyl]benzyl}-2-{3-hydroxy-4-[(2-phenylethyl)amino]-1,1-biphenyl-2-yl}acetamide::Substituted Benzene Analog 51

SMILES NC(=N)c1ccc(CNC(=O)Cc2c(O)c(NCCc3ccccc3)ccc2-c2ccccc2)cc1

InChI Key InChIKey=BMKZZNQBNUXUQB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 14600   

TargetCoagulation factor VII(Human)
Pharmacia

LigandPNGBDBM14600(N-[(4-carbamimidoylphenyl)methyl]-2-{2-hydroxy-6-p...)
Affinity DataIC50: 2.70E+3nMpH: 8.0 T: 2°CAssay Description:Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2007
Entry Details Article
PubMed
TargetProthrombin(Human)
Pharmacia

LigandPNGBDBM14600(N-[(4-carbamimidoylphenyl)methyl]-2-{2-hydroxy-6-p...)
Affinity DataIC50: 6.80E+3nMpH: 8.0 T: 2°CAssay Description:Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Pharmacia

LigandPNGBDBM14600(N-[(4-carbamimidoylphenyl)methyl]-2-{2-hydroxy-6-p...)
Affinity DataIC50: 3.00E+4nMpH: 8.0 T: 2°CAssay Description:Human Factor Xa and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2007
Entry Details Article
PubMed