BDBM14603 N-[(4-carbamimidoylphenyl)methyl]-2-[2,6-difluoro-3-(phenylmethanesulfonamido)phenyl]acetamide::N-{4-[Amino(imino)methyl]benzyl}-2-{3-[(benzylsulfonyl)amino]-2,6-difluorophenyl}acetamide::Substituted Benzene Analog 29b

SMILES NC(=N)c1ccc(CNC(=O)Cc2c(F)ccc(NS(=O)(=O)Cc3ccccc3)c2F)cc1

InChI Key InChIKey=DLWCGMXCEMSQPE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 14603   

TargetProthrombin(Human)
Pharmacia

LigandPNGBDBM14603(N-[(4-carbamimidoylphenyl)methyl]-2-[2,6-difluoro-...)
Affinity DataIC50: 2.69E+4nMpH: 8.0 T: 2°CAssay Description:Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Pharmacia

LigandPNGBDBM14603(N-[(4-carbamimidoylphenyl)methyl]-2-[2,6-difluoro-...)
Affinity DataIC50: 3.00E+4nMpH: 8.0 T: 2°CAssay Description:Human Factor Xa and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2007
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Pharmacia

LigandPNGBDBM14603(N-[(4-carbamimidoylphenyl)methyl]-2-[2,6-difluoro-...)
Affinity DataIC50: 3.00E+4nMpH: 8.0 T: 2°CAssay Description:Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2007
Entry Details Article
PubMed