BDBM14709 1,3-diethyl 2-{[(3-phenylphenyl)amino]methylidene}propanedioate::Diethyl 2-((biphenyl-3-ylamino)methylene)malonate::biphenyl compound 14

SMILES CCOC(=O)C(C=Nc1cccc(c1)-c1ccccc1)C(=O)OCC

InChI Key InChIKey=WHQSBENLMFJXRC-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 14709   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Leeds

LigandPNGBDBM14709(Diethyl 2-((biphenyl-3-ylamino)methylene)malonate ...)
Affinity DataKi:  1.00E+4nM ΔG°:  -6.82kcal/mole IC50: 8.67E+4nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2007
Entry Details Article
PubMed
LigandPNGBDBM14709(Diethyl 2-((biphenyl-3-ylamino)methylene)malonate ...)
Affinity DataKi:  1.28E+4nM IC50: 1.04E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2007
Entry Details Article
PubMed