BDBM147443 US8957093, 297

SMILES C[C@H](NC(=O)c1ccc2n(Cc3ccc(cc3)-c3ccccc3C(O)=O)c(C)c(C)c2c1)c1cccc(c1)C1CC1

InChI Key InChIKey=WFYZRGARXVIIQQ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 147443   

TargetPeroxisome proliferator-activated receptor gamma(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM147443(US8957093, 297)
Affinity DataIC50: 7nMAssay Description:Binding affinity to GST-tagged PPAR-gamma-LBD (unknown origin) after 2 hrs by Lantha screen assay using fluormone Pan-PPAR green probeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM147443(US8957093, 297)
Affinity DataIC50: 10nMAssay Description:The assay was performed according to manufacturer protocol. A mixture of nM GST-PPARG-LBD, 5 nM Tb-GST-antibody, 5 nM Fluormone Pan-PPAR Green, and s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetPeroxisome proliferator-activated receptor gamma(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM147443(US8957093, 297)
Affinity DataEC50:  4.39E+3nMAssay Description:Transactivation of human PPARgamma in HEK293T cells after 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed