BDBM148111 US8962609, DMX-45

SMILES CN(C)CCNC(=O)c1cccc(Nc2nccc(n2)-c2ccc(N3CCCC3)c(c2)C#N)c1

InChI Key InChIKey=ZLRVHQNQVQSHIG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 148111   

TargetSerine/threonine-protein kinase TBK1(Human)
Domainex

US Patent
LigandPNGBDBM148111(US8962609, DMX-45)
Affinity DataIC50: 30nMpH: 7.5Assay Description:Inhibitions studies were performed using a time-resolved fluorescence-based Lanthascreen assay. Phosphorylation of a fluorescein-labelled substrate p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
Go to US Patent

LigandPNGBDBM148111(US8962609, DMX-45)
Affinity DataIC50: 30nMpH: 7.5Assay Description:Inhibitions studies were performed using a time-resolved fluorescence-based Lanthascreen assay. Phosphorylation of a fluorescein-labelled substrate p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
Go to US Patent