BDBM148429 US8962637, 160

SMILES CC(CC(=O)Nc1ccc(C)c(c1)N1CCc2nc(Nc3ccc(OCCN4CCN(C)CC4)cc3)ncc2C1)C(F)(F)F

InChI Key InChIKey=UZICUOYVCKOCLZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 148429   

TargetTyrosine-protein kinase JAK2(Human)
Debiopharm

US Patent
LigandPNGBDBM148429(US8962637, 160)
Affinity DataIC50: 15nMAssay Description:Compounds were screened in the TR-FRET assay for JAK2 and c-Src kinase inhibition. Ultra light poly GT (Perkin Elmer) was used as the substrate for J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Debiopharm

US Patent
LigandPNGBDBM148429(US8962637, 160)
Affinity DataIC50: 66nMAssay Description:Compounds were screened in the TR-FRET assay for JAK2 and c-Src kinase inhibition. Ultra light poly GT (Perkin Elmer) was used as the substrate for J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent