BDBM148980 US8962646, 2

SMILES Oc1c(ccc2C[C@H]3N(CCc4ccccc4)CC[C@@]4(CC(=O)CC[C@@]34O)c12)C(=O)NCCc1ccc(cc1)-c1c[nH]c(=O)[nH]c1=O

InChI Key InChIKey=ZACLASYUKHPVHU-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 148980   

TargetMu-type opioid receptor(Human)
Alkermes

US Patent
LigandPNGBDBM148980(US8962646, 2)
Affinity DataKi:  0.660nM ΔG°:  -12.5kcal/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
US Patent

TargetDelta-type opioid receptor(Human)
Alkermes

US Patent
LigandPNGBDBM148980(US8962646, 2)
Affinity DataKi:  24nM ΔG°:  -10.4kcal/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
US Patent

TargetKappa-type opioid receptor(Human)
Alkermes

US Patent
LigandPNGBDBM148980(US8962646, 2)
Affinity DataKi: >1.00E+3nM ΔG°: >-8.18kcal/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
US Patent