BDBM148982 US8962646, 4

SMILES CN1CC[C@]23CC(=O)CC[C@@]2(O)[C@H]1Cc1ccc(C(=O)NCCc2ccc(cc2)-c2cnc(O)nc2O)c(O)c31

InChI Key InChIKey=CUKMGLMWZGYQHK-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 148982   

TargetMu-type opioid receptor(Human)
Alkermes

US Patent
LigandPNGBDBM148982(US8962646, 4)
Affinity DataKi:  1.30nM ΔG°:  -12.1kcal/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Alkermes

US Patent
LigandPNGBDBM148982(US8962646, 4)
Affinity DataKi:  190nM ΔG°:  -9.16kcal/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent

TargetDelta-type opioid receptor(Human)
Alkermes

US Patent
LigandPNGBDBM148982(US8962646, 4)
Affinity DataKi: >1.00E+3nM ΔG°: >-8.18kcal/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent