BDBM148984 US8962646, 6

SMILES CN1CC[C@]23CC(=C)CC[C@@]2(O)[C@H]1Cc1ccc(C(=O)NCCc2ccc(cc2)-c2c[nH]c(=O)[nH]c2=O)c(O)c31

InChI Key InChIKey=PBXQPVQDVLHYHN-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 148984   

TargetMu-type opioid receptor(Human)
Alkermes

US Patent
LigandPNGBDBM148984(US8962646, 6)
Affinity DataKi:  3.5nM ΔG°:  -11.5kcal/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent

TargetDelta-type opioid receptor(Human)
Alkermes

US Patent
LigandPNGBDBM148984(US8962646, 6)
Affinity DataKi:  97nM ΔG°:  -9.56kcal/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Alkermes

US Patent
LigandPNGBDBM148984(US8962646, 6)
Affinity DataKi:  1.00E+3nM ΔG°:  -8.18kcal/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent