BDBM148987 US8962646, 9

SMILES CN1CC[C@]23CC(=O)CCC2[C@H]1Cc1ccc(C(=O)NCCc2nc4ccccc4[nH]2)c(O)c31

InChI Key InChIKey=VCOJRXQHJIVTBO-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 148987   

TargetMu-type opioid receptor(Human)
Alkermes

US Patent
LigandPNGBDBM148987(US8962646, 9)
Affinity DataKi:  1.70nM ΔG°:  -12.0kcal/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
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TargetDelta-type opioid receptor(Human)
Alkermes

US Patent
LigandPNGBDBM148987(US8962646, 9)
Affinity DataKi:  280nM ΔG°:  -8.93kcal/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Alkermes

US Patent
LigandPNGBDBM148987(US8962646, 9)
Affinity DataKi:  400nM ΔG°:  -8.72kcal/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent