BDBM15008 3-(4-{4-aminofuro[2,3-d]pyrimidin-5-yl}phenyl)-1-(2-fluoro-5-methoxyphenyl)urea::4-amino-5-diarylurea-furo[2,3-d]pyrimidine 8f

SMILES COc1ccc(F)c(NC(=O)Nc2ccc(cc2)-c2coc3ncnc(N)c23)c1

InChI Key InChIKey=JCCJOFRCRNWJTG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 15008   

TargetAngiopoietin-1 receptor(Human)
Glaxosmithkline

LigandPNGBDBM15008(3-(4-{4-aminofuro[2,3-d]pyrimidin-5-yl}phenyl)-1-(...)
Affinity DataIC50: 224nMpH: 7.4 T: 2°CAssay Description:The assay uses purified GST-Tie-2 or GST-6x His-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
LigandPNGBDBM15008(3-(4-{4-aminofuro[2,3-d]pyrimidin-5-yl}phenyl)-1-(...)
Affinity DataIC50: 331nMpH: 7.5 T: 2°CAssay Description:The assay uses purified GST-Tie-2 or GST-6x His-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed