BDBM150784 2-(4-(Dimethylamino)phenyl)-2,3-dihydroquinazolin-4(1H)-one (1h)

SMILES CN(C)c1ccc(cc1)C1NC(=O)c2ccccc2N1

InChI Key InChIKey=MRIZYDSZRRRMPI-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 150784   

TargetCathepsin B(Goat)
Kurukshetra University

LigandPNGBDBM150784(2-(4-(Dimethylamino)phenyl)-2,3-dihydroquinazolin-...)
Affinity DataKi:  1.06E+4nMpH: 6.0Assay Description:Cathepsin B and H were first activated in the presence of thiol activators at pH 6.0 and pH 7.0, respectively. Then, 15 µL of the enzyme solution was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2015
Entry Details Article
PubMed
TargetCathepsin H(Goat)
Kurukshetra University

LigandPNGBDBM150784(2-(4-(Dimethylamino)phenyl)-2,3-dihydroquinazolin-...)
Affinity DataKi:  1.86E+4nMpH: 6.0Assay Description:Cathepsin B and H were first activated in the presence of thiol activators at pH 6.0 and pH 7.0, respectively. Then, 15 µL of the enzyme solution was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2015
Entry Details Article
PubMed