BDBM150885 US8981106, 74

SMILES Fc1ccc(NC(=O)c2ccc(SCc3ccc(o3)C(F)(F)F)nc2)cc1

InChI Key InChIKey=YRGBFGSZPMRYJW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 150885   

TargetC-X-C chemokine receptor type 2(Human)
Syntrix Biosystems

Curated by ChEMBL
LigandPNGBDBM150885(US8981106, 74)
Affinity DataIC50: 5.00E+3nMAssay Description:Antagonist activity at CXCR2 in human PMNs assessed as inhibition of CXCL1-induced intracellular Ca2+ release by fluorescence based calcium flux assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2016
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Syntrix Biosystems

Curated by ChEMBL
LigandPNGBDBM150885(US8981106, 74)
Affinity DataIC50: 5.00E+3nMT: 2°CAssay Description:An in vitro assay showed inhibition of CXCR2-mediated intracellular calcium release. Briefly, human neutrophils were suspended in HBSS- (without Ca2+...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent