BDBM15164 1-[1-({4-[3-phenyl-6-(2H-1,2,3,4-tetrazol-5-yl)quinoxalin-2-yl]phenyl}methyl)piperidin-4-yl]-2,3-dihydro-1H-1,3-benzodiazol-2-one::quinoxaline 16c

SMILES O=c1[nH]c2ccccc2n1C1CCN(Cc2ccc(cc2)-c2nc3ccc(cc3nc2-c2ccccc2)-c2nnn[nH]2)CC1

InChI Key InChIKey=BYLSJFOFBQNZSU-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 15164   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Research Laboratories

LigandPNGBDBM15164(1-[1-({4-[3-phenyl-6-(2H-1,2,3,4-tetrazol-5-yl)qui...)
Affinity DataIC50: 63nMpH: 7.5 T: 2°CAssay Description:Purified recombinant human Akt1, Akt2, and Akt3 proteins were monitored for kinase activity in the presence or absence of Akt inhibitors in a 96-well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2007
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Research Laboratories

LigandPNGBDBM15164(1-[1-({4-[3-phenyl-6-(2H-1,2,3,4-tetrazol-5-yl)qui...)
Affinity DataIC50: 63nMAssay Description:Inhibition of Akt1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Merck Research Laboratories

LigandPNGBDBM15164(1-[1-({4-[3-phenyl-6-(2H-1,2,3,4-tetrazol-5-yl)qui...)
Affinity DataIC50: 65nMAssay Description:Purified recombinant human Akt1, Akt2, and Akt3 proteins were monitored for kinase activity in the presence or absence of Akt inhibitors in a 96-well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2007
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Merck Research Laboratories

LigandPNGBDBM15164(1-[1-({4-[3-phenyl-6-(2H-1,2,3,4-tetrazol-5-yl)qui...)
Affinity DataIC50: 65nMAssay Description:Inhibition of Akt2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
LigandPNGBDBM15164(1-[1-({4-[3-phenyl-6-(2H-1,2,3,4-tetrazol-5-yl)qui...)
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of Akt3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
LigandPNGBDBM15164(1-[1-({4-[3-phenyl-6-(2H-1,2,3,4-tetrazol-5-yl)qui...)
Affinity DataIC50: 1.23E+3nMAssay Description:Purified recombinant human Akt1, Akt2, and Akt3 proteins were monitored for kinase activity in the presence or absence of Akt inhibitors in a 96-well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2007
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM15164(1-[1-({4-[3-phenyl-6-(2H-1,2,3,4-tetrazol-5-yl)qui...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of SGKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed