BDBM152482 (Z-L-Am7(S-)-QA)2 (4)

SMILES O=C(NC(CCCCCSSCCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1cccc2cccnc12)C(=O)Nc1cccc2cccnc12)OCc1ccccc1

InChI Key InChIKey=XQPDEMOFEZWKBH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 152482   

TargetHistone deacetylase 1(Human)
Kyushu Institute of Technology

LigandPNGBDBM152482((Z-L-Am7(S-)-QA)2 (4))
Affinity DataIC50: 8.20nMAssay Description:For the enzyme assay, 10 µL of the enzyme fraction was added to 1 µL of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 µL of histone deacetylase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Kyushu Institute of Technology

LigandPNGBDBM152482((Z-L-Am7(S-)-QA)2 (4))
Affinity DataIC50: 3.40nMAssay Description:For the enzyme assay, 10 µL of the enzyme fraction was added to 1 µL of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 µL of histone deacetylase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
TargetHistone deacetylase 6(Mouse)
Kyushu Institute of Technology

LigandPNGBDBM152482((Z-L-Am7(S-)-QA)2 (4))
Affinity DataIC50: 7.5nMAssay Description:For the enzyme assay, 10 µL of the enzyme fraction was added to 1 µL of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 µL of histone deacetylase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed