BDBM15367 3-(5-Chloro-2,4-dihydroxyphenyl)-4-(4-methoxyphenyl)-5-methyl-1H-pyrazole::4-chloro-6-[4-(4-methoxyphenyl)-5-methyl-1H-pyrazol-3-yl]benzene-1,3-diol::CCT018159 analog 6

SMILES COc1ccc(cc1)-c1c(C)[nH]nc1-c1cc(Cl)c(O)cc1O

InChI Key InChIKey=NOPCVCOFHGDYAB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15367   

TargetHeat shock protein HSP 90-beta(Human)
Vernalis (R&D)

LigandPNGBDBM15367(4-chloro-6-[4-(4-methoxyphenyl)-5-methyl-1H-pyrazo...)
Affinity DataIC50: 150nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed