BDBM154019 US9012443, 12

SMILES COc1cc(ccc1-c1cccc2cc(ccc12)S(=O)(=O)Nc1ncns1)C(F)(F)F

InChI Key InChIKey=VILWNHSACYQVKK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 154019   

LigandPNGBDBM154019(US9012443, 12)
Affinity DataIC50: 10nMAssay Description:293 Cells stably transfected with either Nav 1.7 or Nav 1.5 were recorded in population patch-clamp mode with the IonWorks Quattro automated electrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2015
Entry Details
Go to US Patent

LigandPNGBDBM154019(US9012443, 12)
Affinity DataIC50: 1.16E+4nMAssay Description:293 cells stably transfected with Nav 1.5 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology system acco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2015
Entry Details
Go to US Patent

LigandPNGBDBM154019(US9012443, 12)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells assessed as inhibition of sodium current at holding potential of -125 mV measured for 3 to 5 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2018
Entry Details Article
PubMed
LigandPNGBDBM154019(US9012443, 12)
Affinity DataIC50: 51nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells assessed as inhibition of sodium current at holding potential of -125 mV measured for 3 to 5 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2018
Entry Details Article
PubMed