BDBM154049 US9012443, 42

SMILES COc1cc(ccc1-c1cccc2cc(ccc12)S(=O)(=O)Nc1ccncn1)C(F)(F)F

InChI Key InChIKey=NYXYUZXPPILSFD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 154049   

LigandPNGBDBM154049(US9012443, 42)
Affinity DataIC50: 50nMAssay Description:293 Cells stably transfected with either Nav 1.7 or Nav 1.5 were recorded in population patch-clamp mode with the IonWorks Quattro automated electrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2015
Entry Details
Go to US Patent

LigandPNGBDBM154049(US9012443, 42)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells assessed as inhibition of sodium current at holding potential of -125 mV measured for 3 to 5 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2018
Entry Details Article
PubMed
LigandPNGBDBM154049(US9012443, 42)
Affinity DataIC50: 510nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells assessed as inhibition of sodium current at holding potential of -125 mV measured for 3 to 5 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2018
Entry Details Article
PubMed