BDBM154206 US9012443, 219

SMILES COc1cc(ccc1-c1nc(Cl)cc2cc(ccc12)S(=O)(=O)Nc1nccs1)C(F)(F)F

InChI Key InChIKey=JCLRDJVVHAYXCA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 154206   

LigandPNGBDBM154206(US9012443, 219)
Affinity DataIC50: 170nMAssay Description:293 Cells stably transfected with either Nav 1.7 or Nav 1.5 were recorded in population patch-clamp mode with the IonWorks Quattro automated electrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2015
Entry Details
US Patent

LigandPNGBDBM154206(US9012443, 219)
Affinity DataIC50: 796nMAssay Description:293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology system...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2015
Entry Details
US Patent

TargetSepiapterin reductase(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM154206(US9012443, 219)
Affinity DataIC50: 1.78E+3nMAssay Description:Inhibition of sepiapterin reductase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed