BDBM154387 US9012443, 427

SMILES COc1cc(ccc1-c1nccc2cc(ccc12)S(=O)(=O)Nc1ccc(F)cn1)C(F)(F)F

InChI Key InChIKey=JJDMPIUFRKPKLP-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 154387   

TargetSepiapterin reductase(Human)
Amgen

Curated by ChEMBL

LigandBDBM154387(US9012443, 427)Copy SMILESCopy InChI

Affinity DataIC50: 1.78E+3nMAssay Description:Inhibition of sepiapterin reductase (unknown origin)More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/11/2021
Entry Details Article
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TargetSodium channel protein type 9 subunit alpha(Human)
Amgen

US Patent

LigandBDBM154387(US9012443, 427)Copy SMILESCopy InChI

Affinity DataIC50: 4.42E+3nMAssay Description:293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology system...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/12/2015
Entry Details
Copy BDB DOIUS Patent

Copy reaction URL