BDBM154456 US9012443, 521

SMILES COc1cc(c(Cl)cc1-c1ncnc2cc(ccc12)S(=O)(=O)Nc1ncns1)-c1cccc(F)c1

InChI Key InChIKey=NAAYBGMVDQIEPA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 154456   

LigandPNGBDBM154456(US9012443, 521)
Affinity DataIC50: 19nMAssay Description:293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology system...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2015
Entry Details
Go to US Patent

LigandPNGBDBM154456(US9012443, 521)
Affinity DataIC50: 4.75E+3nMAssay Description:293 cells stably transfected with Nav 1.5 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology system acco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2015
Entry Details
Go to US Patent

LigandPNGBDBM154456(US9012443, 521)
Affinity DataIC50: 19nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells by PatchXpress methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM154456(US9012443, 521)
Affinity DataIC50: 4.75E+3nMAssay Description:Inhibition of Nav1.5 (unknown origin) expressed in HEK293 cells by IonWorks patch-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed