BDBM15495 4-{6-[(3R,4S)-3-amino-4-(2,4,5-trifluorophenyl)pyrrolidin-1-yl]pyrimidin-4-yl}benzoic acid::Pyrrolidine-constrained phenethylamine 29d

SMILES N[C@H]1CN(C[C@@H]1c1cc(F)c(F)cc1F)c1cc(ncn1)-c1ccc(cc1)C(O)=O

InChI Key InChIKey=UTUXDZDQMXRVHI-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15495   

TargetDipeptidyl peptidase 4(Human)
Abbott Laboratories

LigandPNGBDBM15495(4-{6-[(3R,4S)-3-amino-4-(2,4,5-trifluorophenyl)pyr...)
Affinity DataKi:  85nMAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2007
Entry Details Article
PubMed