BDBM15497 (3R,4S)-1-{6-[3-(morpholine-4-sulfonyl)phenyl]pyrimidin-4-yl}-4-(2,4,5-trifluorophenyl)pyrrolidin-3-amine::Pyrrolidine-constrained phenethylamine 29f

SMILES N[C@H]1CN(C[C@@H]1c1cc(F)c(F)cc1F)c1cc(ncn1)-c1cccc(c1)S(=O)(=O)N1CCOCC1

InChI Key InChIKey=SDCAYDSIXAYUNR-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 15497   

TargetDipeptidyl peptidase 4(Human)
Abbott Laboratories

LigandPNGBDBM15497((3R,4S)-1-{6-[3-(morpholine-4-sulfonyl)phenyl]pyri...)
Affinity DataKi:  3.20nMAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2007
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Abbott Laboratories

LigandPNGBDBM15497((3R,4S)-1-{6-[3-(morpholine-4-sulfonyl)phenyl]pyri...)
Affinity DataKi:  4.32E+3nMAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2007
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Abbott Laboratories

LigandPNGBDBM15497((3R,4S)-1-{6-[3-(morpholine-4-sulfonyl)phenyl]pyri...)
Affinity DataKi:  1.75E+4nMAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2007
Entry Details Article
PubMed