BDBM15524 (3R)-1-{6-[(3R,4R)-3-amino-4-(2,4,5-trifluorophenyl)piperidin-1-yl]pyrimidin-4-yl}pyrrolidin-3-ol::(R)-1-(6-((3R,4R)-3-Amino-4-(2,4,5-trifluorophenyl)piperidin-1-yl)pyrimidin-4-yl)pyrrolidin-3-ol::Piperidine-Constrained Phenethylamine 48

SMILES N[C@H]1CN(CC[C@@H]1c1cc(F)c(F)cc1F)c1cc(ncn1)N1CC[C@@H](O)C1

InChI Key InChIKey=OOJZORPUAPQAAZ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 15524   

TargetDipeptidyl peptidase 4(Human)
Abbott Laboratories

LigandPNGBDBM15524((R)-1-(6-((3R,4R)-3-Amino-4-(2,4,5-trifluorophenyl...)
Affinity DataKi:  2.30nMAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2007
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Abbott Laboratories

LigandPNGBDBM15524((R)-1-(6-((3R,4R)-3-Amino-4-(2,4,5-trifluorophenyl...)
Affinity DataKi:  1.97E+4nMAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2007
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Abbott Laboratories

LigandPNGBDBM15524((R)-1-(6-((3R,4R)-3-Amino-4-(2,4,5-trifluorophenyl...)
Affinity DataKi: >3.00E+4nMAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2007
Entry Details Article
PubMed