BDBM15575 (3R)-3-amino-4-(3,4-difluorophenyl)-1-[8-(4-fluorophenyl)-2-(trifluoromethyl)-5H,6H,7H,8H-imidazo[1,2-a]pyrazin-7-yl]butan-1-one::DPP-4 ligand 17

SMILES N[C@@H](CC(=O)N1CCn2cc(nc2C1c1ccc(F)cc1)C(F)(F)F)Cc1ccc(F)c(F)c1

InChI Key InChIKey=WETXVMAIYXHWTN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15575   

TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

LigandPNGBDBM15575((3R)-3-amino-4-(3,4-difluorophenyl)-1-[8-(4-fluoro...)
Affinity DataIC50: 1.40E+3nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed