BDBM15592 CHEMBL374335::N-Methyl,N-(benzyl),N-(pyrrol-2-ylmethyl)amine::benzyl(methyl)(1H-pyrrol-2-ylmethyl)amine::pyrrole inhibitor 7

SMILES CN(Cc1ccc[nH]1)Cc1ccccc1

InChI Key InChIKey=XQZWJHDHWFGAPS-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 15592   

TargetAmine oxidase [flavin-containing] B(Bovine)
Sapienza University of Rome

LigandPNGBDBM15592(N-Methyl,N-(benzyl),N-(pyrrol-2-ylmethyl)amine | C...)
Affinity DataKi:  20nMAssay Description:MAO A and MAO B activities were determined spectrophotometrically using kinuramine as substrates. Fluorimetric measurements were recorded with a Perk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Bovine)
Sapienza University of Rome

LigandPNGBDBM15592(N-Methyl,N-(benzyl),N-(pyrrol-2-ylmethyl)amine | C...)
Affinity DataKi:  20nMAssay Description:Inhibition of bovine brain mitochondrial MAO-B by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Bovine)
Sapienza University of Rome

LigandPNGBDBM15592(N-Methyl,N-(benzyl),N-(pyrrol-2-ylmethyl)amine | C...)
Affinity DataKi:  3.50E+3nM ΔG°:  -7.76kcal/molepH: 7.4 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically using kinuramine as substrates. Fluorimetric measurements were recorded with a Perk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Bovine)
Sapienza University of Rome

LigandPNGBDBM15592(N-Methyl,N-(benzyl),N-(pyrrol-2-ylmethyl)amine | C...)
Affinity DataKi:  3.50E+3nMAssay Description:Inhibition of bovine brain mitochondrial MAO-A by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Bharati Vidyapeeth Deemed University

Curated by ChEMBL
LigandPNGBDBM15592(N-Methyl,N-(benzyl),N-(pyrrol-2-ylmethyl)amine | C...)
Affinity DataKi:  2.85E+8nMAssay Description:Inhibition of MAO-A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed