BDBM156254 US9018391, 16

SMILES C[C@H]1C[C@]2(Cc3ccc(cc3[C@]22N=C(N)N(Cc3ccnc(C)c3)C2=O)C#N)C[C@@H](C)[C@@H]1O

InChI Key InChIKey=NGEOZBVZQJWSEI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 156254   

TargetBeta-secretase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM156254(US9018391, 16)
Affinity DataIC50: 9.40nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
Go to US Patent