BDBM158480 US9029401, 1686

SMILES OC(=O)c1ccc(O[C@@H]2CC[C@@H](CC2)NC(=O)Nc2ccc(OC(F)(F)F)cc2)cc1

InChI Key InChIKey=XDVFKCZZXOGEMN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 158480   

TargetBifunctional epoxide hydrolase 2(Human)
University of California

US Patent
LigandPNGBDBM158480(US9029401, 1686)
Affinity DataIC50: 0.600nMAssay Description:See reference (Jones, P. D.; Wolf, N. M.; Morisseau, C.; Whetstone, P.; Hock, B.; Hammock, B. D. Anal. Biochem. 343:66-75; 2005) for sEH assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2015
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1(Human)
University of California Davis

Curated by ChEMBL
LigandPNGBDBM158480(US9029401, 1686)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human FAAH expressed in baculovirus-infected High Five cells S9 fraction using OMP substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of California

US Patent
LigandPNGBDBM158480(US9029401, 1686)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase expressed in baculovirus-infected High Five cells S9 fraction using CMNPC substrate by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed