BDBM159248 US9034874, 1.5

SMILES Cn1nc(ccc1=O)N1CCC(CC1)OC(=O)N1CCN(CC1)C1CCC1

InChI Key InChIKey=BVUJMFFRMZRNAT-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 159248   

TargetHistamine H3 receptor(Human)
Novartis

US Patent
LigandPNGBDBM159248(US9034874, 1.5)
Affinity DataKi:  1.10nMAssay Description:The potency of compounds of the invention as H3 receptor antagonists can be assessed by measuring the blockade of (R)-alpha-methylhistamine-mediated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2015
Entry Details
Go to US Patent

TargetHistamine H3 receptor(Guinea pig)
Palack£

Curated by ChEMBL
LigandPNGBDBM159248(US9034874, 1.5)
Affinity DataKi:  12nMAssay Description:Inhibition of Guinea Pig Ileum H3RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Palack£

Curated by ChEMBL
LigandPNGBDBM159248(US9034874, 1.5)
Affinity DataKi:  12nMAssay Description:Inhibition of Guinea Pig Ileum H3RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Novartis

US Patent
LigandPNGBDBM159248(US9034874, 1.5)
Affinity DataKi:  25nMpH: 7.5Assay Description:The affinity of compounds of the invention to the H3 receptor can be assessed by measuring displacement of binding of the radioligand [3H]-N-alpha -M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2015
Entry Details
Go to US Patent