BDBM159845 US9040528, 2(a)

SMILES C[C@H]1CN2[C@@H]([C@@H](C)O1)C1(Cc3cc4c(C)noc4c(F)c23)C(=O)NC(=O)NC1=O

InChI Key InChIKey=FWKBFPFKHVTISW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 159845   

TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Astrazeneca

US Patent
LigandPNGBDBM159845(US9040528, 2(a))
Affinity DataIC50: 8.30E+4nMpH: 7.5Assay Description:In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/ml of topologic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2015
Entry Details
Go to US Patent

TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Astrazeneca

US Patent
LigandPNGBDBM159845(US9040528, 2(a))
Affinity DataIC50: 83nMAssay Description:Inhibition of Escherichia coli DNA gyrase using fluorescence-tagged DNA by fluorescenct polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed