BDBM160484 US9682968, Example-27-3b (+)

SMILES COC1CCN(Cc2c(cc(C)c3[nH]ccc23)C2CC2)C(C1)c1ccc(cc1)C(O)=O

InChI Key InChIKey=CKPFEBYAYLCXDR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 160484   

TargetComplement factor B(Human)
Novartis

US Patent
LigandPNGBDBM160484(US9682968, Example-27-3b (+))
Affinity DataIC50: 0.740nMAssay Description:CVF-Bb complex prepared from purified cobra venom factor (1 uM), recombinant human complement factor B (expressed in drosophila cells and purified us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2018
Entry Details
US Patent