BDBM160678 US9045498, 20

SMILES C[C@H]1C[C@H]2[C@@H](CF)SC(N)=N[C@]2(CO1)c1cc(CNCC(F)(F)F)c(F)cc1F

InChI Key InChIKey=DDPFTQRFQMKXNQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 160678   

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM160678(US9045498, 20)
Affinity DataIC50: 68nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent