BDBM162183 US9682995, 82

SMILES Cc1nsc(Nc2cncc(n2)C(F)(F)F)c1C(=O)Nc1ccc(F)c(F)c1

InChI Key InChIKey=QAQNENKIWLGPLT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 162183   

TargetMitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085](Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM162183(US9682995, 82)
Affinity DataIC50: 1.50E+4nMpH: 8.0Assay Description:Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
US Patent

TargetDual specificity protein kinase TTK(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM162183(US9682995, 82)
Affinity DataIC50: 2.00E+4nMpH: 7.7 T: 2°CAssay Description:N-terminally GST-tagged human full length recombinant Mps-1 kinase (purchased from Invitrogen, Karslruhe, Germany, cat. no PV4071) was used. As subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
US Patent