BDBM164220 US9688615, 31

SMILES CC(C)C[C@H](CN)Cc1nc2c(cc(cc2[nH]1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=PETRFKCSWBGTCM-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 164220   

TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Degiacomo, Interim Trustee, Mark G.

US Patent
LigandPNGBDBM164220(US9688615, 31)
Affinity DataIC50: 1.00E+4nMAssay Description:Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
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TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Degiacomo, Interim Trustee, Mark G.

US Patent
LigandPNGBDBM164220(US9688615, 31)
Affinity DataIC50: 4.16E+3nMAssay Description:Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
Go to US Patent

TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Degiacomo, Interim Trustee, Mark G.

US Patent
LigandPNGBDBM164220(US9688615, 31)
Affinity DataIC50: 1.00E+4nMAssay Description:Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
Go to US Patent

TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Human)
Degiacomo, Interim Trustee, Mark G.

US Patent
LigandPNGBDBM164220(US9688615, 31)
Affinity DataIC50: 7.58E+3nMAssay Description:Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
Go to US Patent

TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Human)
Degiacomo, Interim Trustee, Mark G.

US Patent
LigandPNGBDBM164220(US9688615, 31)
Affinity DataIC50: 1.26E+3nMAssay Description:Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
Go to US Patent

TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Human)
Degiacomo, Interim Trustee, Mark G.

US Patent
LigandPNGBDBM164220(US9688615, 31)
Affinity DataIC50: 1.00E+4nMpH: 7.4Assay Description:To assess the potential cardiac liability of compounds at an early stage in the drug discovery process, a Nav1.5 sodium channel screening assay was b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
Go to US Patent

TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Human)
Degiacomo, Interim Trustee, Mark G.

US Patent
LigandPNGBDBM164220(US9688615, 31)
Affinity DataIC50: 2.99E+3nMpH: 7.4Assay Description:To assess the potential cardiac liability of compounds at an early stage in the drug discovery process, a Nav1.5 sodium channel screening assay was b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
Go to US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Degiacomo, Interim Trustee, Mark G.

US Patent
LigandPNGBDBM164220(US9688615, 31)
Affinity DataIC50: 1.00E+4nMpH: 7.4Assay Description:To assess the potential cardiac liability of compounds at an early stage in the drug discovery process, a Nav1.5 sodium channel screening assay was b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
Go to US Patent